HISTORY:
A 71 year old male with history of invasive bladder carcinoma and left ureteral urothelial carcinoma presented with hematuria. CT urogram and a TURBT showed invasive poorly differentiated urothelial carcinoma, high grade, with invasion into the muscularis propria of the left bladder wall.
After resection and radiation/chemotherapy, a worrisome lesion was seen on imaging and a cystoscopy was performed and revealed a sessile bladder lesion > 5cm at the site of the prior resection, along the left lateral bladder.
GROSS:
What is the most likely diagnosis?
- von Brunn’s nests
- Inverted papilloma
- Nested variant of urothelial carcinomas
- Nephrogenic metaplasia
Nested variant of urothelial carcinomas