Date of Presentation:11/23/2021

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Nermeen Chaudhry, BA & Bindu Challa, MD

Prepared by: Nermeen Chaudhry, BA & Bindu Challa, MD

Organ:Liver

HISTORY:

A 40 year old male with a history of focal segmental glomerulosclerosis (diagnosed at 15 years of age) complicated by end-stage renal disease presented with abdominal pain after peritoneal dialysis. MRI abdomen without contrast showed 2.6 cm x 3.6 cm complex cystic mass in interpolar right kidney and and 1.9 cm x 1.6 cm complex cystic mass in lateral mid to lower pole of left kidney. Patient subsequently underwent bilateral radical nephrectomy.

GROSS:

What is the most likely diagnosis?

  1. Clear cell papillary renal cell carcinoma
  2. Acquired cystic disease-associated renal cell carcinoma
  3. Fumarate hydratase deficient renal cell carcinoma
  4. Papillary renal cell carcinoma
  5. Chromophobe renal cell carcinoma
Acquired cystic disease-associated renal cell carcinoma