Anatomical Pathology Interesting Case Conference

Date of Presentation:8/11/2025

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Rebecca Reese, BS, MLS (ASCP)

Prepared by: Rebecca Reese, BS, MLS (ASCP)

Organ:Lymph Node

HISTORY:

Patient is a male in his 60s who presented with a rapidly enlarging non-tender lump in his right groin with associated firmness. The patient then proceeded with excisional lymph node biopsy.

Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue

What is the most likely diagnosis?

  1. Small cell melanoma
  2. Merkel cell carcinoma
  3. Small cell lung carcinoma
  4. Diffuse large B cell lymphoma
Merkel cell carcinoma

CASE SUMMARY