Anatomical Pathology Interesting Case Conference

Date of Presentation:11/23/2021

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Nermeen Chaudhry, BA & Bindu Challa, MD

Prepared by: Nermeen Chaudhry, BA & Bindu Challa, MD

Organ:Liver

HISTORY:

A 40 year old male with a history of focal segmental glomerulosclerosis (diagnosed at 15 years of age) complicated by end-stage renal disease presented with abdominal pain after peritoneal dialysis. MRI abdomen without contrast showed 2.6 cm x 3.6 cm complex cystic mass in interpolar right kidney and and 1.9 cm x 1.6 cm complex cystic mass in lateral mid to lower pole of left kidney. Patient subsequently underwent bilateral radical nephrectomy.

GROSS:

Gross image of liver
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue

What is the most likely diagnosis?

  1. Clear cell papillary renal cell carcinoma
  2. Acquired cystic disease-associated renal cell carcinoma
  3. Fumarate hydratase deficient renal cell carcinoma
  4. Papillary renal cell carcinoma
  5. Chromophobe renal cell carcinoma
Acquired cystic disease-associated renal cell carcinoma

CASE SUMMARY