Date of Presentation:6/27/2024

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Risha Khatri, MD

Organ:Kidney

HISTORY:

male in their 60’swith a Positive Family History of Kidney Cancer (paternal grandmother)

Presented for lower back pain with sciatica and right hip pain

Outside MRI abdomen revealed a left upper renal 2.7 x 2.7 cm mass

No definitive evidence of metastatic disease in the kidney, abdomen or chest

Presents to OSUMC for Left Nephrectomy

GROSS:

Left Renal Mass with Perinephric Fat

Sectioning reveals a 3.4 x 2.7 x 2.3 cm tan-pink, solid, rubbery mass with central hemorrhage (20%) without necrosis or calcification

There is a scant amount of uninvolved renal parenchyma which appears tan, homogeneous, unremarkable

Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue

What is the most likely diagnosis?

  1. Papillary Renal Cell Carcinoma
  2. Nephroblastoma
  3. Metanephric Adenoma
  4. Metanephric-like ALK-rearranged renal cell carcinoma
Metanephric Adenoma