Date of Presentation:6/8/2016

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Keluo Yao, M.D.

Prepared by: Sophia Shaddy, M.D.



The patient is a female in her 40s with a past medical history of chronic interstitial cystitis, overactive bladder, recurrent urinary tract infections, and poorly controlled diabetes mellitus.

A biopsy was taken from her bladder during her cystourethroscopy with injection for chemodenervation procedure.

What is the best diagnosis?

  1. Metastatic papillary renal cell carcinoma
  2. Papilloma
  3. Nephrogenic adenoma (metaplasia)
  4. Papillary urothelial carcinoma, low grade
  5. Papillary urothelial neoplasm of low malignant potential
Nephrogenic adenoma (metaplasia)