Our Division, based in the James Cancer Hospital and OSUWMC Department of Pathology, provides clinical molecular diagnostics for a wide range of cancers and other heritable disorders. Our mission is to provide cutting edge, clinically responsible and cost-effective diagnostics for the patients of Ohio and beyond. Testing is performed for cancer conditions, cardiovascular risk and for inherited genetic disorders.
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Molecular Pathology is a medical specialty that seeks to integrate microscopic findings with the genetic changes associated with diseases such as cancer and inflammatory conditions. Goals of this work in cancer patients include more precise diagnostic classification, improved early detection of cancer and providing help in selecting therapies. Another important goal for Molecular Pathology in some cancers is more sensitive detection of low levels of disease to help guide when to continue or restart treatments to help lower the rates of relapse.
The ongoing challenge of Molecular Diagnostics and Genomic Medicine is to rapidly integrate new knowledge about the function of genes into actionable clinical information to tailor patient treatments. This involves computer-assisted analysis of sequence data and new methods to display results of genetic tests in the medical record. The Bioinformatics group in our laboratories designs data pipelines and analysis tools to promote the diagnostic impact of our genomic testing.