Department of Pathology

Dinesh Ahirwar, PhD

Assistant Professor

Dinesh Ahirwar, PhD

Phone:

614-292-9740

E-mail:

Email Dr. Ahirwar

Office Location:

840 Biomedical Research Tower

Mailing Address:

840 Biomedical Research Tower
460 W 12th Ave
Columbus, OH 43210

Biosketch

Dr. Ahirwar is a Research Assistant Professor in the Department of Pathology, Wexner Medical Center, The Ohio State University. Before joining Ohio State University, he completed his post-doctoral training from School of Medicine, University of Utah, Salt Lake City, Utah. His major research focus is to understand how tumor cells hijack surrounding stromal cells, including fibroblasts, endothelial cells and immune cells, to acquire invasive and metastatic properties. Using genetically modified and spontaneous tumor mouse models, he has shown that cancer associated fibroblasts-derived inflammatory molecule CXCL12 enhances tumor cell intravasation by increasing vascular permeability and expansion of a leaky tumor vasculature, resulting in metastasis to the lungs. Dr. Ahirwar is utilizing pro/anti-inflammatory molecules to develop various immune-based strategies against aggressive and metastatic tumors. Other areas of interest includes clinically relevant in-vivo tumor model development, racial disparity in breast cancer and effect of induced Electric Fields on tumor cells.

Grants

Title: RAGE: A Novel Therapeutic Target against Metastatic and Triple Negative Breast Cancer

Role: Co-Investigator

Sponsor: Department of Defense breakthrough award level 2

Dates: 04/2019 - 03/2022

Academic and Medical Appointments

2019 - presentResearch Assistant Professor, Department of Pathology, The Ohio State University

Education and Training

2011 - 2019 Research Scientist, Department of Pathology, The Ohio State University, Columbus, OH

2010 - 2011 Post-doctoral Fellow, School of Medicine, University of Utah, Salt Lake City, Utah

2005 - 2010 Ph.D., Sanjay Gandhi Postgraduate institute of Medical Sciences, Lucknow, Utter Pradesh, India

2003 - 2005 M.S., Biotechnology, Devi Ahilya University, Indore, Madhya Pradesh, India

2000 - 2003 B.S., Biology, Devi Ahilya University, Indore, Madhya Pradesh, India

Selected Publications

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