Department of Pathology

José J. Otero, MD, PhD

Associate Professor

Jose J. Otero, MD, PhD




Email Dr. Otero

Office Location:

4169 Graves Hall

Mailing Address:

4169 Graves Hall
333 W 10th Avenue
Columbus, OH 43210


I am an attending Neuropathologist at Wexner Medical Center and associate attending physician at The James Cancer Center. These duties include surgical neuropathology and autopsy neuropathology. I also receive consultations from community pathologists principally regarding surgical neuropathology but am also available to interpret neuromuscular and peripheral nerve pathology.

Board Certifications

American Board of Pathology, Anatomic Pathology

American Board of Pathology, Neuropathology

Academic and Medical Appointments

Associate Professor (Tenure Track), The Ohio State University College of Medicine, Department of Pathology

Attending Physician at The Ohio State University Wexner Medical Center and Associate Attending The James Cancer Hospital, Department of Pathology, Division of Neuropathology

Associate Director, Neuropathology Division, The Ohio State University College of Medicine and Wexner Medical Center

Principal Investigator, Developmental Neuropathology Laboratory at The Ohio State University College of Medicine, Division of Neuropathology, Department of Pathology

Member of The Ohio State University Wexner Medical Center, Center for Regenerative Medicine and Cell-Based Therapies and the OSU-James Comprehensive Cancer Center

Member of The Ohio State University Center for Latin American Studies

Adjunct Assistant Professor, The Ohio State University College of Medicine, Department of Neuroscience

Education and Training

2009-2012 Clinical Fellow, California Institute of Regenerative Medicine University of California, San Francisco

2006-2012 Molecular Medicine Fellowship, University of California, San Francisco

2008-2010 Neuropathology Fellowship, University of California, San Francisco, Department of Pathology, Neuropathology Division

2006-2008 Anatomic Pathology, University of California, San Francisco, Department of Pathology

2006 Doctor of Medicine, Northwestern University Feinberg School of Medicine

Selected Publications

Search in PubMed

Book Chapters:


  • Short, A., Czeisler, C., Stocker, B., Cole, S., Otero, J.CA, Winter, J.CA Imaging Cell-Matrix Interactions in Three-Dimensional Collagen Culture Systems (2016) Macromolecular Bioscience, in press.
  • Kaya, B., Goceri, E., Gygli, P., Czeisler, C., Gurcan, M.CA, Otero, JJCA Objective quantification of PTBP1 as a biomarker to identify recurrent glioma. PLOS-One, in press
  • Goceri, E., Kaya, B., Elder, B., Puduvalli, V., Otero, J.CA, Gurcan, M.CA Quantitative Validation of Anti-PTBP1 Antibody for Diagnostic Neuropathology Use: Image Analysis Approach. International Journal of Numerical Methods in Biomedical Engineering. In press
  • Czeisler C, Short A.M., Nelson T, Gygli P, Ortiz C, Catacutan FP, Lannutti J, Winter J, Otero JJCA. Surface Topography During Neural Stem Cell Differentiation Regulates Cell Migration and Cell Morphology. Journal of Comparative Neurology in press.
  • Gygli, P., Chang, J., Gokozan, H., Catacutan, F., Schmidt, T., Kaya, B., Goksel, M., Baig, F., Chen, S., Griveau, A., Michowski, W., Wong, M., Kamalakannan, P., Sicinski, P., Nelson, R., Czeisler, C., Otero, J.J. Cyclin A2 promotes DNA repair in the brain during both development and aging. Aging, in press.
  • Moreira, T.CA, Takakura, A., Czeisler, C., Otero, J.J. Respiratory and autonomic dysfunction in congenital central hypoventilation syndrome. Journal of Neurophysiology in press.
  • Gallego-Perez, D.*, Otero, J.*CA, Czeisler, C., Ma, J., Ortiz, C., Gygli, P., Catacutan, F., Gokozan, H., Cowgill, A., Sherwood, T., Ghatak, S., Malkoc, V., Zhao, X., Liao, W., Gnyawali, S., Wang, X., Adler, A., Leong, K., Wulff, B., Wilgus, T., Askwith, C., Khanna, S., Rink, C., Sen, C. CA, Lee CA. Deterministic Transfection Drives Efficient Nonviral Reprogramming and Uncovers Reprogramming Barriers. Nanomedicine. In press
  • Gokozan, H.N., Baig, F., Corcoran, S., Catacutan, F.P., Gygli, P.E., Takakura, A.C., Moreira, T.S., Czeisler, C., Otero, J.J. “Area postrema undergoes dynamic postnatal changes in mice and humans. Journal of Comparative Neurology. In press.
  • Fauzi M, Gokozan HN, Elder B, Puduvalli VK, Pierson CR, Otero JJCA, Gurcan MNCA, “A multi-resolution textural approach to diagnostic neuropathology reporting,” Journal of Neurooncology, 2015 Sep;124(3):393-402.
  • Grodecki, J., Short, A.R., Winter, J.O., Rao, S.S., Winter, J.O., Otero, J.J., Lannutti, J.J., and Sarkar, A. (2015) Glioma-astrocyte interactions on white matter tract-mimetic algiend electrospun nanofibers. Biotechnology Prog, 2015, June 2917. Epup ahead of print.
  • Nobuta, H., Cilio, M.R., Danhaive, O., Tsai, H.H., Tupal, S., Chang, S.M., Murnen, A., Kreitzer, F., Bravo, V., Czeisler, C., Gokozan, H.N., Gygli, P., Bush, S., Weese-Mayer, D.E., Conklin, B., Yee, S.P., Huang, E.J., Gray, P.A., Rowitch, D., Otero, J.J., 2015. Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome. Acta neuropathologica. August, 2015, volume 130 (2): 171-83.
  • Chang, J., Leung, M., Gokozan, H.N., Gygli, P.E., Catacutan, F.P., Czeisler, C., Otero, J.J. “Mitotic Events in Murine Cerebellar Granule Progenitor Cells that Expand Cerebellar Surface Area are Critical for Normal Cerebellar Cortical Lamination” Journal of Neuropathology and Experimental Neurology, March 2015 - Volume 74 - Issue 3 - p 261–272
  • Mathsyaraja, H., Thies, K., Taffany, D.A., Deighan, C., Liu, T., Pecot, T., Yu, L., Fernandez, S.A., Shapiro, C., Otero, J.J., Timmers, C., Lustberg, M., Chalmers, J., Leone, G., Ostrowski, M.C.CA, “CSF1-ETS2 Induced microRNA in Myeloid Cells Promote Metastatic Tumor Growth” Oncogene, 2014, Sept 22 doi: 10.1038
  • Mohammad Faizal Ahmad Fauzi1,5, Hamza Gokozan2, Brad Elder3, Vinay Puduvalli4, Jose J. Otero2, Metin N. Gurcan1. Classification of Glioblastoma and Metastasis for Neuropathology Intraoperative Diagnosis: A Multi-resolution Textural Approach to Model the Background. SPIE Medical Imaging - Digital Pathology Conference Publication (2014).
  • Otero, J.J., Ilona Kalaszczynska, Wojciech Michowski, Michael Wong, Patrick Edwin Gygli, Hamza Numan Gokozan1, Amélie Griveau, Junko Odajima4, Catherine Czeisler, Fay Patsy Catacutan, Alice Murnen, Ulrich Schüler, Piotr Sicinski, and David Rowitch, Cerebellar Cortical Lamination and Foliation Require Cyclin A2 Dev Biol. 2014 Jan 15;385(2):328-39.
  • Rao, S, DeJessus, J, Short, A., Otero, J.J., Sarkar, A., Winter, J. Glioblastoma behaviors in 3D collagen-hyaluronan composite hydrogels. ACS Applied Materials and Interfaces (2013), ACS Appl Mater Interfaces. 2013 Oct 9;5(19):9276-84.