Date of Presentation:8/21/2025
Attending pathologist: Anil Parwani, MD, PhD, MBA
Presented by: Rebecca Reese, BS, MLS (ASCP)
Prepared by: Rebecca Reese, BS, MLS (ASCP)
Organ:Prostate
HISTORY:
Patient is a male in his 50’s with history of adenocarcinoma of the prostate s/p treatments of external beam radiation therapy (EBRT) and 2-years of androgen deprivation therapy who presented with PSA elevation following testosterone recovery. The patient proceeded with MRI-guided prostate biopsy.
What is the most likely diagnosis?
- Prostatic adenocarcinoma with radiation changes
- Prostatic adenocarcinoma, Gleason Grade 3+4=7
- Androgen deprivation effect
- Ductal adenocarcinoma of the prostate
Prostatic adenocarcinoma with radiation changes