Date of Presentation:10/26/2021

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Ankush Patel, MBBS and Bindu Challa MD

Prepared by: Ankush Patel, MBBS and Bindu Challa MD

Organ:Bladder

HISTORY:

A 60 year old male presents with gross hematuria of 2 months duration. Computed tomography (CT) urogram of abdomen and pelvis showed a soft tissue nodule measuring 1.3 cm x 1.1 cm within posterior aspect of bladder. Transurethral resection of bladder tumor (TURBT) was done on follow up.

GROSS:

The specimen is designated "deep bladder tumor" and consists of an aggregate of tan-pink, rubbery, cauterized tissue fragments measuring in aggregate 2.4 x 1.5 x 0.5 cm.

What is the most likely diagnosis?

  1. Pleomorphic giant cell carcinoma of bladder
  2. Metastatic pleomorphic giant cell carcinoma of prostate
  3. Osteoclast-rich undifferentiated carcinoma
  4. Sarcomatoid carcinoma
  5. Melanoma
Pleomorphic giant cell carcinoma of bladder