Date of Presentation:10/26/2021

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Ankush Patel, MBBS and Bindu Challa MD

Prepared by: Ankush Patel, MBBS and Bindu Challa MD

Organ:Bladder

HISTORY:

A 60 year old male presents with gross hematuria of 2 months duration. Computed tomography (CT) urogram of abdomen and pelvis showed a soft tissue nodule measuring 1.3 cm x 1.1 cm within posterior aspect of bladder. Transurethral resection of bladder tumor (TURBT) was done on follow up.

GROSS:

The specimen is designated "deep bladder tumor" and consists of an aggregate of tan-pink, rubbery, cauterized tissue fragments measuring in aggregate 2.4 x 1.5 x 0.5 cm.

Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue

What is the most likely diagnosis?

  1. Pleomorphic giant cell carcinoma of bladder
  2. Metastatic pleomorphic giant cell carcinoma of prostate
  3. Osteoclast-rich undifferentiated carcinoma
  4. Sarcomatoid carcinoma
  5. Melanoma
Pleomorphic giant cell carcinoma of bladder

CASE SUMMARY