Date of Presentation:2/18/2025

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Dr Akansha Deshwal, Dr Himani Kumar, Dr Sambit K Mohanty

Organ:Bladder

HISTORY:

A male in his 60s with a past medical history of bladder cancer, atrial fibrillation and BPH (benign prostatic hyperplasia).

The patient underwent multiple bladder instrumentation/procedures (TURBT, cystourethroscopy, ureteroscopy, ureteroneocystostomy, instillation of anticarcinogenic agent in the bladder)

Most recent cystoscopy revealed a papillary area over right lateral bladder wall.

CT Urogram showed bladder wall thickening more notable on the right posterior lateral wall.

GROSS:

We received multiple tan pink soft tissue pieces measuring 0.5 x 0.4 x 0.3 cm in aggregate.

Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue

What is the most likely diagnosis?

  1. Nephrogenic Adenoma of Bladder
  2. Urothelial Papilloma
  3. Papillary urothelial neoplasm with low malignant potential
  4. Low-grade papillary urothelial carcinomas
Nephrogenic Adenoma of Bladder