Date of Presentation:12/10/2021

Attending pathologist: Anil V. Parwani, MD, PhD, MBA

Presented by: Saba Shafi, MD

Prepared by: Saba Shafi, MD



A 72-year-old female who presents in consultation for incidental left renal mass. CT scan shows an enhancing left renal mass with a central stellate scar. Thus, both RCC and oncocytoma on the differential. Complicating this is a possible new diagnosis of cirrhosis, with signs of liver nodularity and portal hypertension detected on the referring CT scan. The patient also has incidental colonic thickening. A renal biopsy was done for the renal mass.


What is the most likely diagnosis?

  1. Oncocytic papillary RCC
  2. Eosinophilic clear cell RCC
  3. Eosinophilic variant of chromophobe RCC
  4. Oncocytoma