Date of Presentation:12/20/2021

Attending pathologist: Wei Chen, MD, PhD

Presented by: Saba Shafi, MD

Prepared by: Saba Shafi, MD

Organ:Small Intestine


A 36-year-old male with no past medical history who initially presented with progressively worsening abdominal pain and distension. CT AP was demonstrative of a large mass within the central portion of the abdomen measuring 24.6 x 13.7 x 21.7 cm. This encased or was intimately associated with a mildly dilated loop of small bowel within the left lower quadrant measuring 3.9 cm in caliber. Concerning for malignancy including gastrointestinal stromal tumor, spindle cell neoplasm, and lymphoma.


What is the most likely diagnosis?

  1. Myofibromatosis
  2. Sclerosing mesenteritis/idiopathic retroperitoneal fibrosis
  3. Mesenteric desmoid-type fibromatosis
  4. Gastrointestinal stromal tumor (GIST)
Mesenteric desmoid-type fibromatosis