Date of Presentation:9/20/2022

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Muhammad Abdulwaasey, MBBS

Prepared by: Nishant Rangwani, BS & Jacob Portnoff, BS



59 year-old male with history of diabetes mellitus presented with renal mass.

Ct chest of abdomen/pelvis with and without contrast shows heterogeneous enhancing exophytic mass arising from the right inferior renal pole with areas of internal hypoattenuation that could represent areas of necrosis measuring approximately 10.0 x 9.0 x 9.6 cm previously 9.9 x 9.2 x 9.5 cm.

Patient subsequently underwent right robotic radical nephrectomy.


Well circumscribed, solitary lesion of a grayish-yellow color.

Focal areas of necrosis and hemorrhaging.

Cystic areas are also present.

What is the most likely diagnosis?

  1. Renal cell carcinoma post neuroblastoma
  2. Tuberous sclerosis complex associated renal cell carcinoma
  3. Epithelioid angiomyolipoma
  4. Eosinophilic solid and cystic renal cell carcinoma
  5. Clear cell renal carcinoma
  6. Chromophobe renal cell carcinoma, eosinophilic type
Eosinophilic solid and cystic renal cell carcinoma