Date of Presentation:11/20/2020

Attending pathologist: Anil Parwani, MD, PhD

Presented by: Jennifer Ziebell, MD

Prepared by: Jennifer Ziebell, MD



63 year old female presented with abdominal discomfort, gross hematuria, and inability to void. MRI of the pelvis revealed a bladder mass measuring 12.5 x 7.9 x 4.1 cm. Cystourethroscopy revealed a pan urethral tumor, papillary in appearance, which extended to the bladder.

What is the most likely diagnosis?

  1. Dedifferentiated liposarcoma
  2. High grade osteosarcoma, extraskeletal
  3. Undifferentiated pleomorphic sarcoma
  4. Urothelial carcinoma with osseous metaplasia
High grade osteosarcoma, extraskeletal