HISTORY:
A male in his 70s presented with gross hematuria to ER. CT evaluation of the pelvis revealed a bladder mass and prostatic urethra lesion. Cystourethroscopy and TURBT revealed a bladder tumor which extended to the prostatic urethra.
Patient has a history of colon cancer which he underwent partial sigmoid colectomy and adjuvant pelvic chemoradiation in 2008.
No evidence of recurrence for the last 12 years.
GROSS:
Multiple pieces of gray-tan tissue with yellow calculi received from posterior superficial bladder tumor measuring 1.5 x 1.4 x 0.8cm in aggregate. Prostatic lesion light tan tissue fragments received measuring 1.0 x 0.6 x 0.4 cm in aggregate. Posterior deep bladder tumor pieces also received measuring 0.7 x 0.5 x 0.4 cm. Finally, four pieces of light tan tissue measuring 0.2 – 0.4 cm in greatest dimension received labeled small satellite tumors.
No gross images since this case is coming from an outside hospital originally.
What is the most likely diagnosis?
- Epithelioid hemangioendothelioma
- High grade invasive urothelial carcinoma, sarcomatoid features
- Epithelioid angiosarcoma
- Metastatic colorectal carcinoma
- Metastatic melanoma