Date of Presentation:2/25/2021

Attending pathologist: Anil Parwani, MD, PhD

Presented by: Bindu Challa, MD

Prepared by: Bindu Challa, MD

Organ:Bladder

HISTORY:

A male in his 60s presented with gross hematuria. Cystourethroscopy revealed a bladder tumor at the dome, posterior wall and left lateral wall. He was followed up with transurethral resection of bladder tumor (TURBT).

GROSS:

The specimen is designated "large volume multifocal bladder tumors (solid and papillary)" and consists of an aggregate of irregularly-shaped, tan/pink soft tissue fragments with cautery present which measures 6.1 x 5.6 x 1.1 cm.

What is the most likely diagnosis?

  1. Lymphoma
  2. Urothelial carcinoma with lymphoepithelioma-like features
  3. Paraganglioma of urinary bladder
  4. Urothelial carcinoma with small cell/neuroendocrine features and conventional features
  5. Urothelial carcinoma with large cell/neuroendocrine features
Urothelial carcinoma with small cell/neuroendocrine features and conventional features