Date of Presentation:3/25/2021

Attending pathologist: Anil Parwani, MD, PhD

Presented by: Ruhani Sardana, MBBS

Prepared by: Ruhani Sardana, MBBS

Organ:Liver

HISTORY:

A man in late 40s presented with complaints of gross hematuria and flank pain.

Non-contrast CT revealed a 7 cm lobulated mass in the anterior aspect of the right kidney and a nonspecific 2.4 cm hypo-attenuated lesion in the right upper lobe of the liver. No significant enlargement of retroperitoneal lymph nodes.

MRI showed heterogeneous lobulated renal mass as well as a liver mass.

GROSS:

A well-circumscribed, irregularly lobulated mass measuring 7.0 x 6.2 x 5.8 cm located in the middle pole of the kidney

Approximately 30% of the mass was necrotic

Invading the renal vein, adherent to the vessel wall

Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue

What is the most likely diagnosis?

  1. Neuroblastoma
  2. Desmoplastic Small Round Cell Tumor
  3. Ewing Sarcoma / Primitive Neuroectodermal Tumor
  4. Lymphoma
Ewing Sarcoma / Primitive Neuroectodermal Tumor