Date of Presentation:4/26/2021

Attending pathologist: Anil Parwani, MD, PhD

Presented by: Marlon Szczepaniak, BS

Prepared by: Marlon Szczepaniak, BS

Organ:Testis

HISTORY:

A 56 y/o male during workup for an original presentation of alcoholic cirrhosis and lymphadenopathy, had also presented with enlarged lymph nodes in the retrocrural and para-aortic regions. Following a PET scan revealing retroperitoneal and para-aortic lymphadenopathy, a retroperitoneal lymph node biopsy was performed to find a minute cluster of malignant cells with unknown origin. A CT was performed, revealing a vague slightly hypoechoic polylobulated lesion on the inferior aspect of the left testicle measuring 1.2 x 1.7 x 1.0 cm. Denied having any testicular complaints.

GROSS:

The specimen is designated "left orchiectomy" and consists of a 39.0 gram left orchiectomy specimen. The testis measures 4.0 x 1.8 x 1.7 cm. The spermatic cord measures 8.0 x 1.7 cm. The specimen is bivalved to reveal a firm, tan, centrally located mass that measures 1.8 x 1.3 x 1.1 cm. The mass measures greater than 5 cm from the spermatic cord margin. The mass does not grossly involve the tunica albuginea, hilar fat, rete testis, or epididymis. The remaining testicular parenchyma is tan-white, pallor, and strings with ease.

Gross image of testis
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue

What is the most likely diagnosis?

  1. Sarcoidosis
  2. Non-Hodgkin's B-cell Lymphoma
  3. Metastatic Seminoma
  4. Leydig Cell Tumor
Metastatic Seminoma