Date of Presentation:4/26/2021

Attending pathologist: Anil Parwani, MD, PhD

Presented by: Ruhani Sardana, MBBS

Prepared by: Ruhani Sardana, MBBS

Organ:Heart

HISTORY:

A female in late 50s, with history of Hashimoto thyroiditis, hypertension and hyperlipidemia came for general well- being checkup.

A murmur was found on cardiac examination. ECHO imaging showed mild mitral insufficiency and an incidental finding of an asymptomatic mass in the Right Atrium measuring 2.75 x 3.7 cm.

After 6 months, the patient came back for a follow- up visit. MRI of heart showed an increase in the size of the Right atrial mass: 4.2 x 3.4 cm with no obstruction to the Right Atrial flow inlet. The mass was surgically excised.

GROSS:

Yellow-tan colored mass measuring 4.2 x 3.4 cm. No areas of hemorrhage or necrosis seen.

Table describing heart IHC findings
Gross image of heart
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue

What is the most likely diagnosis?

  1. Amyloidosis
  2. Cardiac myxoma
  3. Light Chain Deposition disease
  4. Rhabdomyosarcoma
Light Chain Deposition disease