HISTORY:
A male patient in his 70s presents with non-radiating, sharp, right-sided lumbar pain. Computed tomography abdomen and pelvis showed mildly enhancing lesion in upper pole of right kidney measuring 4.6 cm x 3.1 cm and Computed tomography chest showed several osteolytic lesions and T10 compression fracture. He was followed up with a biopsy of renal mass.
GROSS:
The specimen is designated "right renal mass" and consists of four tan-red soft tissue cores ranging from 0.3-0.9 cm in length x 0.1 cm in diameter.
CDX2, SOX10, Ck20, PAX8, p63, TTF1, CAIX, AE1/AE3, CK7, Melan A stains were also done and read as negative.
What is the most likely diagnosis?
- Renal cell carcinoma with sarcomatoid features
- Anastomosing hemangioma
- Hemagioendothelioma
- Primary Renal Angiosarcoma
- Epithelioid angiomyolipoma
Primary Renal Angiosarcoma