Date of Presentation:5/21/2021

Attending pathologist: Anil Parwani, MD, PhD, MBA

Presented by: Jennifer Ziebell, MD

Prepared by: Jennifer Ziebell, MD

Organ:Prostate

HISTORY:

57 year old male with a past medical history of low testosterone (on supplementation) who presented with increased nocturia and weaker urinary stream that developed over the past two months. PSA increased from 2.38 ng/mL to 4.45 ng/mL over those two months. The patient decided to proceed with a prostate biopsy.

GROSS:

Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue
Microscopic image possibly detecting cancerous areas in human tissue

What is the most likely diagnosis?

  1. Prostatic adenocarcinoma, Gleason score 4+3=7
  2. High grade prostatic intraepithelial neoplasia (HGPIN)
  3. Intraductal carcinoma of the prostate
  4. Prostatic adenocarcinoma, Gleason score 3+4=7
Intraductal carcinoma of the prostate

CASE SUMMARY