Abhay Satoskar, MD, PhD
Professor and Vice Chair
Phone:
E-mail:
Mailing Address:
M258 Evans Hall
520 King Avenue
Columbus, OH 43210
Biosketch
Abhay Satoskar, MD, PhD is a Professor in the Division of Experimental Pathology. He comes to Pathology from the Department of Microbiology at The Ohio State University. Dr. Satoskar earned his PhD in the Department of Immunology, University of Strathclyde in Glasgow, UK and his MD from the Department of Pathology, King Edward VII Memorial Hospital, University of Bombay in Bombay, India. Dr. Satoskar’s research interests are immunology and infectious disease with a focus on parasite immunology.
Grants
Title: Prevention and Treatment of Breast Cancer and Its Metastasis by targeting Macrophage Migration Inhibitory Factor (MIF)
Role: PI
Sponsor: CDMRP/BCRP/DOD
Academic and Medical Appointments
2010-present Professor (tenured), Departments of Pathology and Microbiology, The Ohio State University, Columbus, OH
2010-present Professor, Department of Molecular Virology, Immunology & Medical Genetics (MVIMG), The Ohio State University
2014-present Visiting Scientist, School of Medicine, University of Colombo, Sri Lanka
Education and Training
1996-1998 Postdoctoral Research Fellow, Department of Immunology and Infectious Diseases, Harvard School of Public Health
1998-2000 Postdoctoral Associate, Immunology, The Ohio State University Department of Pathology, Columbus, OH
1992-1996 Ph.D., Department of Immunology, University of Strathclyde, Glasgow, UK
1989-1992 Resident, Department of Pathology, King Edward VII Memorial Hospital, University of Bombay, Bombay, India
1983-1988 M.B., B.S., King Edward VII Memorial Hospital, University of Bombay, Bombay, India
Selected Publications
Books Edited:
- “Pathogenesis of leishmaniasis: Future strategies for control, prevention and treatment” Edited by Satoskar AR and Durvasula R. Springer (to be published in December 2013)
- “Medical Parasitology”, Edited by Satoskar, AR, Simon, G, Tsuji, M and Hotez, P. Landes Bioscience, TX (Published in November 2009).
Book Chapters:
- Lezama-Davila CM, Satoskar AR and Marquez-Issac AP. General mechanisms of tissue injury in parasitic infections. In “Parasitic Diseases of the Lung”. 2013. Ed. Barrios R and Haque AK., Springer-Verlag Berlin, Germany
- Tuladhar R, Dong R, Varikuti S, David JR and Satoskar AR* Role of macrophage migration inhibitory factor (MIF) in parasitic diseases. In “Biology of MIF”. 2011. Ed Rick Bucala, World Scientific, Singapore.
- Alexander, J., Irving, K., Snider, H, and Satoskar, AR. Sex differences in response to parasites. In “Sex hormones and Immunity to Infection”. 2009. Eds Sabra Klein and Craig Roberts, Springer, Heidelberg, Germany.
- Lezama-Davila, CM, David, JR, and Satoskar AR. Cutaneous leishmaniasis. In “Medical Parasitology”. 2009. Ed. Satoskar AR, Simon G, Tsuji M and Hotez P. Landes Bioscience, TX.
- Cummings, H, Rodriguez-Sosa M, and Satoskar AR. Hydatid Disease. In “Medical Parasitology”. 2009. Ed. Satoskar AR, Simon G, Tsuji M and Hotez P. Landes Bioscience, TX.
- Cummings, H, Terrazas LI, and Satoskar AR. Taeniasis and cysticercosis. In “Medical Parasitology”. 2009. Ed. Satoskar AR, Simon G, Tsuji M and Hotez P. Landes Bioscience, TX.
- Lezama-Davila, CM, Issac-Marquez, AP., and Satoskar, AR. Immunoregulation of Chiclero’s ulcer. In “Advances in the Immunobiology of Parasitic Diseases”. 2008. Ed. Luis Terrazas, Research Signpost, Trivandrum, Kerala, India
- Barbi, J., Snider, H.M., and Satoskar, AR. The role of chemokines in Leishmaniasis In “Advances in the Immunobiology of Parasitic Diseases”. 2008. Ed. Luis Terrazas, Research Signpost, Trivandrum, Kerala, India
- Snider, H, Lezama-Davila, C, Terrazas, LI, and Satoskar, AR. MIF in parasitic and helmithic infections. In “MIF: A Most Interesting Factor”. 2006. Ed. Richard Bucala. World Scientific Publishing/Imperial College Press, UK.
- Fingerle-Rowson G., Satoskar, AR, and Bucala R. Macrophage Migration Inhibitory Factor (MIF)-deficient mice. In “Cytokine Knockouts”. 2002. Ed. Giamila Fantuzzi, Humana Press, New Jersey
- Alexander J, and Satoskar, AR. Leishmaniasis: does Interleukin-13 (IL-13) play a significant role in the disease process? In “Interleukin-13”. 2002. Ed. Frank Brombacher. Landes Bioscience, Texas.
Publications:
- Naman, BC, Gromovsky, AD, Vela, CM, Fletcher, JN, Gupta, G., Varikuti, S., Zhu, X., Emilia, M., Chai, H., Werbovetz, K., Satoskar, AR and Kinghorn, AD. Antileishmanial and Cytotoxic Activity of Some Highly Oxidized Abietane Diterpenoids from the Bald Cypress, Taxodium distichum. J. Nat. Prod.
- Siewe, N., Yakubu, AA, Satoskar AR and Friedman A. Immune response to infection by Leishmania: A mathematical model. Mathematical Biosciences
- Natarajan G, Terrazas, C., Oghumu S., Varikuti, S., Byrd, JC and Satoskar AR*. A Tec kinase BTK inhibitor ibrutinib promotes maturation and activation of dendritic cells. OncoImmunology
- Collier, M.A., Peine, K. J., Gautam, S., Oghumu, S., Varikuti, S., Bortheh, H., Papenfuss, T. L., Satoskar, A.R, Bachelder, E.M., and Ainslie, K.M. Host-mediated Leishmania donovani treatment using AR-12 encapsulated in accelerated dextran microparticles. Int. J. Pharmaceutics
- Terrazas, CA, Varikuti, S, Kimble, J., Moretti, E., Boyaka, P., and Satoskar AR*. Interleukin 17A promotes susceptibility to experimental visceral leishmaniasis caused by Leishmania donovani. FASEB J 2015; Nov 18. pii: fj.15-277202
- Zhao, H., Oghumu, S., Powell, C.A., Satoskar AR., Li, D. Y., and Ganju, R. K. Endothelial Robo4 suppresses breast cancer growth and metastasis through regulation of tumor angiogenesis Mol. Can. 2015; Oct 28. pii: S1574-7891(15)00185-4.
- Gupta, G., Peine, KJ, Abdelhamid D., Snider H, Shelton A., Rao L., Kotha S., Huntsman A., Varikuti S., Oghumu S., Naman B., Pan L, Parinandi NL, Pappenfuss TL, Kinghorn AD, Bachelder E., Ainslie KM, Fuchs JR and Satoskar AR*. A novel sterol isolated from a plant used by Mayan traditional healers is effective in treatment of visceral leishmaniasis caused by Leishmania donovani. ACS Infect. Dis. 2015; 1 (10), pp 497–506.
- Natarajan G, Terrazas, C., Oghumu S., Varikuti, S., Dubovsky, J, Byrd, JC and Satoskar AR*. Ibrutinib promotes Th17 cell differentiation by modulating dendritic cell function. OncoImmunology 2015; DOI:10.1080/2162402X.2015.1057385