E411 Doan Hall
410 W. 10th Ave
Columbus, OH 43210
Link to director's bio
The Ohio State University Wexner Medical Center is home to one of the world’s leading digital pathology programs.
Daily over 2,400 slides are digitized and made instantly available to our pathologists who use them for primary diagnosis, consultation, education, and research. In 2018, Ohio State became the first site in the United States to utilize digital pathology for primary diagnosis. Today, most of our sign-outs are digital.
Digital allows our pathologists to share their knowledge and skills to help patients around the state and across the globe. The use of digital images allows us to erase time and distance and provide pathology review in real time hundreds or even thousands of miles away.
We are proud to also be a leader in deploying quantitative image analysis (QIA), machine learning, and artificial intelligence to produce diagnoses for patients that are dramatically faster, more comprehensive, and more accurate than ever previously possible. We work with our partners to develop, test, and implement the tools that will transform pathology in the 21st Century.
Digital pathology has also enabled our teams to expand our research capabilities. Our research lab assists scientist with using digital resources and tools to probe the nature, causes, consequences, and treatment of disease in ways never before possible. Digital allows our researchers to assemble cohorts more rapidly, inquire of larger volumes of cases, and interrogate specimens more deeply, faster, and more accurately than ever before.
As a consequence of our endeavors, we manage one of the world’s largest collections of whole slide images (WSI). Ohio State is home to almost 2.7 million WSIs, representing over 280,000 patients, and every imaginable tissue and disease type.
Scanning of a 1" x 3" slide to create digital whole slide image at 20x magnification
Scanning of a 1" x 3" slide to create digital whole slide image at 20x magnification
Creation of unique algorithm beyond simple measurement of a single feature
Quantification of features (region of interest size, nuclear staining, marker staining, nuclear size, etc.) for a digital image (non-TMA)
Slide annotation/marking
Extraction of a JPEG image from a digital whole slide image at requested magnification (1x-20x)
Quantification of features (nuclear staining, marker staining, nuclear size, etc.) per core for a tissue microarray of more than 100 cores
Quantification of features (nuclear staining, marker staining, nuclear size, etc.) per core for a tissue microarray of 100 or fewer cores
The OSUCCC – James Digital Pathology team of experts is dedicated to detecting and diagnosing cancer accurately and quickly. Our team’s mission is to work with researchers and physicians to provide answers to research questions—simple and complex—using the most sophisticated technology available.
The digital pathology process begins with whole-slide imaging, or scanning conventional glass slides and then using sophisticated technology to join consecutive images digitally into a single, whole image—replicating the information on the glass slide.
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