Department of Pathology

Jieli (Shirley) Li, MD, PhD

Associate Professor-Clinical

Portrait of Jieli (Shirley) Li, MD, PhD
  • Office Location:
  • E314 Doan Hall
  • 410 W. 10th Ave.
  • Columbus, OH 43210

Biosketch

Jieli Shirley Li, MD, PhD, is an Associate Clinical Professor of Pathology at The Ohio State University College of Medicine. She is Director of Clinical Pathology Services and Co-Director of the Clinical Chemistry & Toxicology Laboratory at the Ohio State Wexner Medical Center. Dr. Li obtained her MD and PhD degrees from the Shanghai Jiao-Tong University School of Medicine and completed her fellowship training in clinical chemistry at the MD Anderson Cancer Center. Her professional interests center around enhancing laboratory tests for the in vitro diagnosis, prognosis, and treatment planning of cancer, endocrine disorders, and cardiovascular diseases.

Dr. Li has authored over 50 scientific articles and contributing as an Ad Hoc reviewer for 20 different scientific journals. She also plays an important role in participating in guidelines writing for the Clinical & Laboratory Standards Institute (CLSI) and serving on the Expert Panel Committee of CLSI. Furthermore, Dr. Li contributes to the field as an inspector and inspection team leader for the College of American Pathologists (CAP) and is actively involved with CAP's Chemistry Committee.

Academic and Medical Appointments

2024-Present Associate Clinical Professor of Pathology at The Ohio State University College of Medicine

2019-2024 Assistant Clinical Professor of Pathology at The Ohio State University College of Medicine

2025-Present Director of Clinical Pathology Services at the Ohio State Wexner Medical Center

2025-Present CLIA/CAP Director of Stefanie Spielman Comprehensive Breast Center at the Ohio State Wexner Medical Center

2025-Present CLIA/CAP Director of Martha Morehouse Outpatient Care at the Ohio State Wexner Medical Center

2025-Present Division Director of Laboratory Administration and Compliance at the Ohio State Wexner Medical Center

2025-Present Division Director of Outreach Services at the Ohio State Wexner Medical Center

2019-Present Co-Director of Clinical Chemistry&Toxicology Laboratory at the Ohio State Wexner Medical Center

Education and Training

2017-2019 Clinical Chemistry Fellow, Department of Pathology, University of Texas MD Anderson Cancer Center

2011-2014 Post-Doctoral Fellow, Department of Physiology and Biophysics, University of Illinois at Chicago

2009-2011 Post-Doctoral Fellow, Department of Medical Physiology, Texas A&M University Health Science Center

2004-2009 Ph.D. in Endocrinology, Shanghai Jiao-Tong University School of Medicine, China

1997-2002 M.D. in Clinical Medicine, Shanghai Jiao-Tong University School of Medicine, China

Selected Publications

Search in PubMed

  • Li J*, Patton A, Lee JKY, Scheidegger M, Azaryan I, Sipos J, Nabhan F, Jones J, Algeciras-Schimnich A, Ringel MD*. Defining the Functional Sensitivity for The Siemens Atellica Calcitonin Assay: Insight from A Single-center Study. Endocr Pract. 2024 Aug 26:S1530-891X(24)00656-6. [PMID: 39197746] [*corresponding author]
  • Li J*, Hatten-Beck M, Lee JKY, Hoofnagle AN*. Insights into insulin analog cross-reactivity: a comparative study of Siemens Atellica and LC-MS/MS. Endocrine. 2024 Jul 19. [PMID: 39030378] [*corresponding author]
  • Alkhalaileh H, Wei R, Cordero Rivera A, Goksel M, Lee JKY, Mazzaferri Jr. E, Jones J, Li J. Evaluation of Age and Sex Differences on Contemporary Versus High-sensitivity Troponin I Measurement in Hospitalized Patients. J Clin Med. 2024 Apr 21;13(8):2428. [PMID: 38673701]
  • Xu R, Zhang S, Li J*, Zhu J*. Plasma and serum metabolic analysis of healthy adults shows characteristic profiles by subjects' sex and age. Metabolomics 2024 Mar 16;20(2):43. [PMID: 38491253] [*corresponding author]
  • Huang R, Shi J, Wei R, Li J. Challenges of insulin-like growth factor-1 testing. Crit Rev Clin Lab Sci. 2024 Aug;61(5):388-403. [PMID: 38323343]
  • Alkhalaileh H, Wei R, Lee JKY, Jones J, Li J. Relationship between TSH and Free Thyroxine in Outpatient Cancer Patient Population. Endocrine. 2023 Nov;82(2):319-325. [PMID: 37286745]
  • Franks CE, Li J, Martinez M, Farnsworth CW, Jones PM, Grenache DG, Meng QH, Gronowski AM. Utility of commercially available quantitative hCG immunoassays as tumor markers in trophoblastic and non-trophoblastic disease. Clin Chem. 2023 May 19:hvad045. [PMID: 37205831]
  • Mahler K, Kerlin R, Jones J, Li J. Effects of Heparin on pH, Ionized calcium, Lactate and Potassium in Venous Whole Blood in Evacuated Tubes. Lab Med. 2023 Sep 5;54(5):e157-e160. [PMID: 37095624]
  • Lee JKY, Cradic K, Singh RJ, Jones J, Li J. Discordance of insulin-like growth factor-1 results and interpretation on four different platforms. Clin Chim Acta. 2022 Dec 14;539:130-133. [PMID: 36528048]
  • Zha L*, Li J*, Krishnan SM, Brennan MR, Zhang YV, Povse P, Kerlin R, Shively K, Oleksik F, Williams J, Sykes E, Sun Q. New Diagnostic Cutoffs for Adrenal Insufficiency after Cosyntropin Stimulation using Abbott Architect Cortisol Immunoassay. Endocr Pract. 2022 Jul;28(7):684-689. [PMID: 35487459] [*co-first author]
  • Li J, Rietschlin J, Miller I, Weber C, Scheidegger M, Barringer S, Kerlin R, Williams J*. Evaluation of the Preanalytical Interference of Hemoglobin, Bilirubin or Lipids on Therapeutic Drug Monitoring Assays on Beckman Coulter AU Analyzers. Lab Med. 2022 Mar 7;53(2):172-176. [PMID: 34436600]
  • Scarl RT, Balada-LIasat JM, Nowacki N, Solaro RJ, Williams J*, Li J*. Myocardial Injury, Inflammation and Prothrombotic Response Are Associated with Outcomes of COVID-19 Patients. Ann Cardiol Vasc Med. 2021: 4(1); 1041. [*corresponding author]
  • Walker C, Shuster A, Weber C, Gebhardt K, Scheidegger M, Swartzwelder J, Williams J*, Li J*. Comparison of the Siemens Atellica BRAHMS and the Abbott Architect BRAHMS Procalcitonin Assays. Ann Clin Lab Sci. 2021 Mar;51(2):241-244 [PMID: 33941564][*corresponding author]
  • Yang HS*, Shemesh A*, Li J*, Xie T, Apple FS, Williams J, Zhao Z, Steel AD. No increase in the incidence of cardiac troponin I concentration above the 99th percentile by Siemens Centaur high-sensitivity compared to the contemporary assay. Clin Biochem. 2020 Dec 6:S0009-9120(20)30905-X. [PMID: 33296707][*co-first author]
  • Li J, Chang HM, Banchs J, Araujo DM, Hassan SA, Wagar EA, Yeh ETH, Meng QH. Detection of subclinical cardiotoxicity in sarcoma patients receiving continuous doxorubicin infusion or pre-treatment with dexrazoxane before bolus doxorubicin. Cardiooncology. 2020 Jan 2;6:1. [PMID: 32154027]
  • Li J, Ma J, Wagar EA, Liang D, Meng QH. A rapid ultra-performance LC-MS/MS assay for determination of serum unbound fraction of voriconazole in cancer patients. Clin Chim Acta. 2018 Nov;486:36-41. [PMID: 30016626]
  • Li J, Wagar EA, Meng QH. Comprehensive Assessment of Biotin Interference in Immunoassays. Clin Chim Acta. 2018 Oct 5;487:293-298 [PMID: 30296442]