Department of Pathology

Rana Naous, MD

Associate Professor-Clinical

portrait of Rana Naous

Phone:

614-366-3714

E-mail:

Email Dr. Naous

Office Location:

Rhodes Hall S305E
410 W. 10th Ave.
Columbus, OH 43210

Biosketch

Rana Naous, MD, is an Associate Professor-Clinical in the Anatomic Pathology Branch at The Ohio State University Wexner Medical Center (OSUWMC). Dr. Naous is a board-certified surgical pathologist specializing in Bone and Soft Tissue pathology and Cytopathology.

Dr. Naous’s research focuses on implementation of cyto/histo-morphology, cytogenetics and molecular testing as diagnostic and prognostic tools in bone and soft tissue tumors. Dr. Naous has authored over 65 peer-reviewed publications.

Board Certifications

American Board of Anatomic and Clinical Pathology-2014; American Board of Cytopathology-2016; American Board of Hematopathology-2017

Academic and Medical Appointments

2025-Present Associate Professor of Pathology at Ohio State University Wexner Medical Center, Columbus, OH

2020-2025 Assistant Professor of Pathology, Bone and Soft Tissue Pathology Fellowship Director, Pittsburgh PA

2017-2020 Assistant Professor of Pathology, SUNY Upstate Medical University, Syracuse, NY

Education and Training

2016-2017 Hematopathology Fellow, SUNY Upstate Medical University, Syracuse NY

2015-2016 Cytopathology Fellow, SUNY Upstate Medical University, Syracuse, NY

2014-2015 Bone and Soft Tissue pathology Fellow, Cleveland Clinic, Cleveland, OH

2010-2014 Resident, Anatomic and Clinical Pathology, University Hospital Cleveland, Cleveland, OH

2004-2008 Doctor of Medicine (MD), American University of Beirut, Beirut, Lebanon

Selected Publications

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  • Batson B, Hegazy S, Naous R. Superficial ALK-Rearranged Myxoid Spindle Cell Neoplasm With Aberrant Keratin Expression and a Rare Gene Fusion Partner. Am J Dermatopathol. 2025 Sep 16. doi: 10.1097/DAD.0000000000003132. Epub ahead of print. PMID: 40956860.
  • Neyaz A, Chrisinger JSA, Korentzelos D, Jalluri GD, Naous R, Wald AI, Ulici V, Wangsiricharoen S, Alani A, Rottmann D, Dehner CA, Dermawan JK, Perry K, John I. Perinephric Myxoid Pseudotumor of Fat: A Series of 29 Cases Demonstrating Inconsistent Associations With Underlying Kidney Disease. Am J Surg Pathol. 2025 Sep 5. doi: 10.1097/PAS.0000000000002467. Epub ahead of print. PMID: 40903830.
  • Torres S, Naous R. Cytopathologic diagnosis of cerebrospinal fluid metastasis from solid tumors: a 10-year institutional review. J Am Soc Cytopathol. 2025 Jul 31:S2213-2945(25)00088-2. doi: 10.1016/j.jasc.2025.07.009. Epub ahead of print. PMID: 40850903.
  • Noor Z, Hegazy S, Naous R. Efficacy and Cost-Effectiveness of MDM2 Fluorescence In Situ Hybridization (FISH) in Morphologically Atypical Spermatic Cord Lipomas. Cureus. 2025 Jul 13;17(7):e87852. doi: 10.7759/cureus.87852. PMID: 40799874; PMCID: PMC12342841.
  • Romanish M, Naous R. Metastatic tumors to the pancreas: An institutional experience. Ann Diagn Pathol. 2025 Dec;79:152528. doi: 10.1016/j.anndiagpath.2025.152528. Epub 2025 Jul 8. PMID: 40638990.
  • Grove J, Naous R. CIC::DUX4 Sarcoma With Preferentially Expressed Antigen in Melanoma (PRAME) Immunopositivity. Cureus. 2025 May 31;17(5):e85154. doi: 10.7759/cureus.85154. PMID: 40599504; PMCID: PMC12208817.
  • Li WT, Bhogal S, Gong MF, Hoffman AP, Zou T, Gajda M, Naous R, Schoedel K, Andrews C, Cordle A, Lee S, Weiss KR, McGough RL 3rd. Rating the Efficacy of Diagnostic Imaging Studies Conducted for the Workup of Musculoskeletal Tumors. J Am Acad Orthop Surg Glob Res Rev. 2025 Mar 24;9(4):e25.00015. doi: 10.5435/JAAOSGlobal-D-25-00015. PMID: 40184606; PMCID: PMC11936625.
  • Naous R. Reliability of cytopathology and ancillary testing modalities in the diagnosis of extramedullary hematopoiesis and sclerosing extramedullary hematopoietic tumor: a 10-year institutional experience. J Am Soc Cytopathol. 2025 Jul-Aug;14(4):236-242. doi: 10.1016/j.jasc.2025.02.001. Epub 2025 Mar 9. PMID: 40157822.
  • Hegazy S, Naous R. Molecular Characterization of Vascular Transformation of Lymph Node Sinuses via Oncomine Comprehensive Assay. Int J Surg Pathol. 2025 Sep;33(6):1373-1382. doi: 10.1177/10668969251314122. Epub 2025 Feb 25. PMID: 40007116.
  • Neyaz A, Mohebnasab M, Hahn E, Rosenbaum J, da Gama Lobo L, Karunamurthy A, John I, Weiss KR, Schoedel K, Chiosea SI, Naous R. Low-grade myxoid spindle cell neoplasm with novel gene fusions involving MAP3K3 and MAP3K8 kinases: a report of two cases. Histopathology. 2025 Apr;86(5):832-836. doi: 10.1111/his.15388. Epub 2024 Dec 9. PMID: 39653366.
  • Naous R, Hegazy S. Low-Level MDM2 Amplification by FISH: An Institutional Experience With a Diagnostic Dilemma. Int J Surg Pathol. 2025 Jun;33(4):891-900. doi: 10.1177/10668969241295353. Epub 2024 Nov 20. PMID: 39563528.
  • Bedell M, Naous R. Primary osseous tumors of the orbit. Virchows Arch. 2025 Mar;486(3):445-455. doi: 10.1007/s00428-024-03975-6. Epub 2024 Nov 12. PMID: 39528823.
  • Neyaz A, Abukhiran I, Naous R. Sporadic NF1-Mutated Inflammatory Polyps of the Colon: A Case Report and Brief Literature Review. Genes Chromosomes Cancer. 2024 Oct;63(10):e70001. doi: 10.1002/gcc.70001. PMID: 39422328.
  • Dashti NK, Perret R, Balzer B, Naous R, Michal M, Dermawan JK, Antonescu CR. Vascular Neoplasms With NFATC1/C2 Gene Alterations : Expanding the Clinicopathologic and Molecular Characteristics of a Distinct Entity. Am J Surg Pathol. 2024 Apr 1;48(4):487-496. doi: 10.1097/PAS.0000000000002175. Epub 2024 Jan 8. PMID: 38189436; PMCID: PMC11591551.
  • Zilla ML, John I, Naous R. Loss of Histone H3K27 Trimethylation (H3K27me3) Expression as a Potential Diagnostic Pitfall in Sarcomatoid Carcinoma. Int J Surg Pathol. 2024 Sep;32(6):1089-1094. doi: 10.1177/10668969231215819. Epub 2023 Nov 23. PMID: 37997394.
  • Naous R, Skaugen JM, Zilla ML, Burgess M, John I. VIM::KMT2A rearranged sarcoma: a rare emerging entity. Histopathology. 2023 Nov;83(5):822-824. doi: 10.1111/his.15028. Epub 2023 Aug 14. PMID: 37575084.
  • Leckey BD Jr, John I, Wald A, Naous R. Expanding the Molecular Genetic Spectrum of Bone and Soft Tissue Fibrosarcomas: An Institutional Experience. Int J Surg Pathol. 2022 Apr;30(2):145-150. doi: 10.1177/10668969211037861. Epub 2021 Aug 12. PMID: 34382874.
  • Naous R, Kobayashi K, Khurana KK. Dynamic Telecytopathology-Guided Rapid On-Site Assessment of Percutaneous Image-Guided Fine-Needle Aspiration of Hepatic Lesions: An Institutional Review of 178 Cases. Telemed J E Health. 2020 Aug;26(8):961-966. doi: 10.1089/tmj.2019.0185. Epub 2019 Oct 29. PMID: 31657674.
  • Hudson S, Wang D, Middleton F, Nevaldine BH, Naous R, Hutchison RE. Crizotinib induces apoptosis and gene expression changes in ALK+ anaplastic large cell lymphoma cell lines; brentuximab synergizes and doxorubicin antagonizes. Pediatr Blood Cancer. 2018 Aug;65(8):e27094. doi: 10.1002/pbc.27094. Epub 2018 Apr 26. PMID: 29697184.Hudson S, Wang D, Middleton F, Nevaldine BH, Naous R, Hutchison RE. Crizotinib induces apoptosis and gene expression changes in ALK+ anaplastic large cell lymphoma cell lines; brentuximab synergizes and doxorubicin antagonizes. Pediatr Blood Cancer. 2018 Aug;65(8):e27094. doi: 10.1002/pbc.27094. Epub 2018 Apr 26. PMID: 29697184.Hudson S, Wang D, Middleton F, Nevaldine BH, Naous R, Hutchison RE. Crizotinib induces apoptosis and gene expression changes in ALK+ anaplastic large cell lymphoma cell lines; brentuximab synergizes and doxorubicin antagonizes. Pediatr Blood Cancer. 2018 Aug;65(8):e27094. doi: 10.1002/pbc.27094. Epub 2018 Apr 26. PMID: 29697184.Hudson S, Wang D, Middleton F, Nevaldine BH, Naous R, Hutchison RE. Crizotinib induces apoptosis and gene expression changes in ALK+ anaplastic large cell lymphoma cell lines; brentuximab synergizes and doxorubicin antagonizes. Pediatr Blood Cancer. 2018 Aug;65(8):e27094. doi: 10.1002/pbc.27094. Epub 2018 Apr 26. PMID: 29697184.
  • Naous R, Zhang S, Valente A, Stemmer M, Khurana KK. Utility of Immunohistochemistry and ETV6 (12p13) Gene Rearrangement in Identifying Secretory Carcinoma of Salivary Gland among Previously Diagnosed Cases of Acinic Cell Carcinoma. Patholog Res Int. 2017;2017:1497023. doi: 10.1155/2017/1497023. Epub 2017 Apr 6. PMID: 28484662; PMCID: PMC5397614.