Department of Pathology

Ashley Patton, DO, PhD

Assistant Professor-Clinical

Portrait of Ashley Patton, DO, PhD
  • Office Location:
  • Starling Loving M366
  • 320 W 10th Ave.
  • Columbus, OH 43210

Biosketch

Ashley Patton, DO, PhD, is an Assistant Professor in the Divisions of Bone and Soft Tissue and Molecular Pathology at the Ohio State University Wexner Medical Center.

Dr. Patton earned her DO from the Heritage College of Osteopathic Medicine and her PhD from the Molecular and Cellular Biology Program at Ohio University. She completed her AP/CP residency at the Ohio State University Wexner Medical Center followed by fellowships in Bone and Soft Tissue at the Cleveland Clinic and Molecular Genetic Pathology at Memorial Sloan Kettering Cancer Center.

Her research interests include understanding inflammatory pathways contributing to the pathogenesis of soft tissue sarcomas and mesenchymal neoplasms of the gynecological tract.

Board Certifications

Anatomic and Clinical Pathology, American Board of Pathology

Molecular Genetic Pathology, American Board of Pathology

Academic and Medical Appointments

2026-Present Assistant Professor, Bone and Soft Tissue and Molecular Divisions, Department of Pathology, OSUWMC, Columbus, OH

Education and Training

2025-2026 Fellowship, Molecular and Genetic Pathology, Memorial Sloan Kettering Cancer Center, NY

2024-2025 Fellowship, Bone and Soft Tissue, Cleveland Clinic Foundation, OH

2020-2024 Anatomic and Clinical Pathology Residency, The Ohio State University Wexner Medical Center, OH

2012-2020 DO, Ohio University Heritage College of Osteopathic Medicine, OH

2014-2018 PhD, Ohio University, OH

Selected Publications

Search in PubMed

  • Pan X, Patton A, Chang YS, Stevens R, Mohamed N, Hunt M, Chappell D, Hu Y, Miller C, Zhao W, Avenarius M, Jones D, Optimizing bioinformatic workflows to extract clinically usable gene expression data from targeted tumor RNA sequencing panels: comparison with total RNA-seq in cancer samples. Bioinformatics Advances. 2026 July 13;6(1):vbag197, PMID:42529613. DOI:10.1093/bioadv/vbag197
  • Haight PJ, Esnakula A, Eiedinger CJ, Suarez AA, Gillespie J, Patton A, Chassen A, Cohn DE, Cosgrove CM, Molecular characterization of mixed-histology endometrial carcinoma provides prognostic and therapeutic value over morphologic findings. NPJ Precision Oncology. 2025 Feb 8;9(1):41. PMID:39922938. DOI:10.1038/s41698-025-00803-1
  • Patton A, Horn N, Upadhaya P, Sarchet P, Pollock RE, Oghumu S, Iwenofu OH, Targeted transcriptomic analysis of well-differentiated and dedifferentiated liposarcoma reveals multiple dysregulated pathways including glucose metabolism, TGF-β, and HIF-1 signaling, Frontiers in Oncology. 2024. Nov 26:14:1456071, PMID:39659782. DOI:10.3389/fonc.2024.1456071
  • J Li, Patton A, Lee JKY, Scheidegger M, Azaryan I, Sipos JA, Nabhan F, Jones J, Algeciras-Schimnich A, Ringel MD, Defining the Functional Sensitivity for the Siemens Atellica Calcitonin Assay: Insight From a Single-Center Study. Endocrine Practice. 2024. Aug 26:S1530-891X(24)00656-6. PMID:39197746. DOI:10.1016/j.eprac.2024.08.007
  • McCall KD, Walter D, Patton A, Thuma J, Courreges M, Palczewski G, Goetz DJ, Bergmeier S, Schwartz, FL. Therapeutic effects of a novel small molecule inhibitor of inflammation in a male C57BL/6J mouse model of obesity-induced NAFLD/MAFLD. Journal of Inflammation Research. 2023. Nov16:16:5339-5366. PMID:38026235. DOI:10.2147/JIR.S413565
  • Patton A, Dermawan JK, Current Updates in Sarcoma Biomarker Discovery: Emphasis on Next-Generation Sequencing-based Methods. Pathology. 2023. DOI:10.1016/j.pathol.2023.10.015
  • Patton A, Ilaslan H, Armstrong SM, Bakhshwin A, Cheng YW, Minhas F, Fritchie KJ. Keratin-positive giant cell-rich tumor of bone harboring an HMGA2::NCOR2 fusion: two cases, including a patient with metastatic disease, and review of the literature. Int. J Surg Pathol. 2023. Jul 17:10668969231185076. PMID: 37461232. DOI: 10.1177/10668969231185076
  • Patton A, Billings SD, Fritchie KJ. Myoepithelioma, myoepithelioma-like, and chondroid soft tissue tumors arising at acral sites: A review. Human Pathology. 2023. Apr11;S0046-8177(23)00082-5. PMID:37054781. DOI:10.1016/j.humpath.2023.04.003
  • Wu Q, Lafuse W, Kumar N, Saljoughian N, Zian A, Patton A, Ganesan L., Yount J. Rajaram M, Influenza A Virus Modulates ACE2 Expression and SARS-CoV-2 Infectivity in Human Cardiomyocytes. iScience. 2022. Dec.22;25(12):105701. PMID: 36474635. DOI. 10.1016/j.isci.2022.105701
  • Patton A, Speeckaert A, Xiaoyan C, Iwenofu O. H. A novel IRF2BP2::CDX2 gene fusion in digital intravascular spindle cell myoepithelioma of soft tissue: An enigma. Genes Chromosomes Cancer. 2022. Nov 29; online ahead of print. PMID: 36448218. DOI: 10.1002/gcc.23108
  • Patton A, Wakely P. E. Pleomorphic hyalinizing angiectatic tumor: FNA analysis of a rare entity and review of the literature. Journal of the American Society of Cytopathology. 2023. Mar-Apr;12(2):136-141. PMID: 36494276. DOI: https://doi.org/10.1016/j.jasc.2022.11.001
  • Patton A, McKenney J, Alruwaii F, Arispe Angulo K, Fuller L, Calvaresi E, Billings S, Goldblum J, Fritchie K. Paratesticular dedifferentiated liposarcoma with epithelioid features: a diagnostic pitfall. Int J Surg Pathol. 2022. Sep 15; online ahead of print. PMID: 36113458. DOI: 10.1177/10668969221120780
  • Patton A, Oghumu S, Iwenofu O. H. A SS18::NEDD4 cutaneous spindled and epithelioid sarcoma: A hitherto unclassified cutaneous sarcoma, resembling epithelioid sarcoma with aggressive clinical behavior. Genes Chromosome Cancer. 2022. Oct;61(10):635-40. PMID: 35639915. DOI: 10.1002/gcc.23071
  • Javaid, S, Patton A, Tinoco G, Oghumu S, Iwenofu O. H. Metastatic sporadic paraganglioma with EWSR1:: CREM gene fusion: A unique molecular profile that expands the phenotypic diversity of the molecular landscape of the EWSR1::CREM gene fusion positive tumors. Gene Chromosomes Cancer. 2023. Feb;62(2):85-92. PMID: 36083250. DOI: 10.1002/gcc.23094
  • Shafi S, Patton A, Rogers A, Grignol V, Oghumu S, Iwenofu O. H. Sporadic mesenteric desmoid-type fibromatosis with “Double-Hit” T41A and S45P mutation profile, an extremely rare event: clinically relevant or much ado about nothing? Precision Cancer Medicine. 2022. DOI: 10.21037/pmc-22-2
  • Vazzano J, Patton A, Tinoco G, Iwenofu O. H. Primary Intranodal Epithelioid Hemangioendothelioma with Molecular Confirmation. Int J Surg Pathol. 2022 Jan 31:10668969211070174. PMID: 35098778. DOI: 10.1177/10668969211070174
  • Parkinson B, Patton A, Rogers A, Farhadi F, Oghumu S, Iwenofu O.H. Intraneural Nodular Fasciitis of the Femoral Nerve with A Unique CTNNB1::USP6 Gene Fusion: Apropros of a Case and Review of Literature. International Journal of Surgical Pathology. 2021. PMID: 35175167. DOI: 10.1177/10668969221080064
  • Patton A, Bridge J, Liebner D, Iwenofu O. H. A YAP1::TFE3 Cutaneous Low-Grade Fibromyxoid Neoplasm: A Novel Entity! Genes Chromosomes Cancer. 2021. Epub ahead of print. PMID: 3487592. DOI:10.1002/gcc.23018
  • Qaiser, S, Brodsky L, Barth R, Leier C, Buja L, Yildiz V, Mo X, Allenby P, Moore S, Ivanov L, Chen W, Thomas D, Rivera A, Gamble D, Hartage R, Mao G, Sheldon J, Sinclair D, Vazzano J, Zehr B, Patton, A; Brodsky, S. An unexpected paradox: wall shear stress in the aorta is less in patients with severe atherosclerosis regardless of obesity. Cardiovascular Pathology. 2020. Epub; PMID: 33242600. DOI:10.1016/j.carpath.2020.107313
  • Patton A, Church T, Wilson C, Thuma J, Goetz D, Berryman D, List E, Schwartz F, McCall K. Phenylmethimazole Abrogates Diet-Induced Inflammation, Glucose Intolerance and NAFLD. Journal of Endocrinology. Epub. 2018; PMID: 29666152. DOI:10,1530/JOE-180078