Debra Zynger, MD
Director
Anil Parwani, MD,
PhD, MBA
Swati Satturwar MD
Gary Tozbikian, MD
The Division of Genitourinary Pathology consists of Dr. Debra Zynger (director), Dr. Anil Parwani, Dr. Swati Satturwar, and Dr. Gary Tozbikian.
The division is responsible for an annual volume of 4200 cases with 70% in-house, non-consult cases. In-house, non-consult cases consist of a wide diversity and large oncologic volume including 370 nephrectomy, 250 robotic prostatectomy, 130 adrenalectomy, 120 cystectomy, 60 orchiectomy and 10 penectomy resections per year. Cases are complex and advanced tumors are not infrequent. For example, 45% of robotic prostatectomies are classified as pT3. Over 700 needle core prostate biopsies are performed at our institution with a diagnosis of carcinoma rendered in >60% of cases.
Diagnostic immunohistochemical tests that have been implemented in the past decade and utilized by the Division of Genitourinary Pathology include AR, CAIX, CD44s, FH, GATA3, laminin, NKX3.1, OCT3/4, PAX8, p40, SALL4, SDHB, SF1, TFE3, CK5/p53 double stain, CK5/CK7 double stain and an inhouse cocktail of AMACR/p63/CK5. Diagnostic florescence in situ hybridization tests that have been implemented in the past decade include analysis of 3p/3q ratio for the work up of clear cell renal cell carcinoma.
The Division of Genitourinary Pathology participates in several monthly interdisciplinary meetings attended by Pathology, Urology, Genitourinary Oncology and Radiation Oncology including Urologic Oncology Tumor Board and Genitourinary Oncology Clinical Trial Update.
Subspecialty sign-out allows for in-depth teaching opportunities. Trainees specializing in Pathology or related disciplines such as Urology can take a 1-month medical student or resident rotation in Genitourinary Surgical Pathology. The division also participates in the required 3rd year medical student Surgical Pathology clerkship experience and the 2nd year medical student Career Exploration.
The Genitourinary Pathology division is actively involved in research projects and frequently collaborates with members of Urology, Oncology, Radiation Oncology and Radiology.
